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MatTek's patented EpiDerm™ System consists of normal, human-derived epidermal 

keratinocytes (NHEK) which have been cultured to form a multilayered, highly 

differentiated model of the human epidermis. These "ready-to-use" tissues, also 

known generically as Normal Human-3D (NHu-3D), are cultured on specially 

prepared cell culture inserts using serum free medium, attain levels of 

differentiation on the cutting edge of in vitro skin technology. Ultrastructurally, the 

EpiDerm Skin Model closely parallels human skin, thus providing a useful in vitro 

means to assess dermal irritancy and toxicology.

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